CURRENT LAB MEMBERS
Marie is interested in studying the formation and evolution of patterns in the skin. She completed her PhD in avian developmental biology in the laboratory of Pr. Marcelle at the University of Marseille (France) in 2007, and then moved as a postdoc in the laboratory of Dr. Hoekstra at Harvard University, where she studied the developmental bases of color pattern variation in rodents. Since 2013, she is a Young Research Group Leader at the Collège de France (CIRB). She also works a few weeks a year as a naturalist guide in the Arctic and Antarctica.
Magdalena received her Ph.D. degree in 2011 from the Paris XIII University. She was advised by Pr. Beaudry in the laboratory of Pr. Richalet and in close collaboration with Pr. Darribère, and studied muscle differentiation in hypoxia in xenopus. She then worked during two years as a Research Assistant Lecturer at Paris V University, before joining the laboratory of Dr. Perron at Paris-Sud University for a first postdoc, where she focused on retina regeneration in amphibia. Magdalena joined the lab as a postdoctoral fellow in Febrary 2015 where she adapts her micromanipulation skills from her previous developmental studies in amphibia to work on the origin of positional factors shaping large color domains in zebra finches. She is also the lab memory: what would we do without her organising skills??
Nicolas completed his PhD in the laboratory of Dr. Yasuo at Nice University (Marine research station of Villefranche-sur-Mer). He characterized the function of Ephrin signaling pathways during neural fate specification and pigments cells formation in Ascidians. Nicolas joined the laboratory as a postdoc in February 2015: he is interested in the developmental regulation of periodic patterning in juveniles of galliformes and Ratites. Teaming up with Richard, he links models of pattern formation to variation in natural phenotypes. His ultimate goal is to uncover the mystery of intricate geometric patterning. When not in the lab, you can find Nicolas riding his bike or fishing, or (albeit not so often in Paris) wearing a pair of skis.
Richard studied at the Ecole Normale Supérieure of Rennes where he passed his agrégation in mathematics. He discovered mathematical biology during an internship in Jonathan Touboul's laboratory at the Collège de France in 2013, where he designed models describing neural activity. He carried on with a Master in Mathematics applied to Life Sciences (Paris-Sud University) and a PhD in the lab, co-advised by Marie Manceau, Jonathan Touboul and Benoît Perthame (UPMC). Richard defended his thesis on July 10th 2019, and is now looking for postdoc opportunities!
His work in the lab mainly consists in conceiving models describing developmental mechanisms underlying the formation of color and appendage patterns in birds of the Passeriformes, Galliformes, and Sphenisciformes orders. Richard is also the official lab cook, often feeding his lab mates with his famous "tarte au citron".
Camille joined the lab in January 2016 as part of her second year of Master's rotation student to study the origin of color domains in zebra finches using lineage techniques such as quail-zebra finch grafts and long-term electroporation. She is now performing her PhD; her project aims at describing the cell and tissue dynamics occurring during the formation of plumage macro- and micro-pattern. She recently became our "graft master", helping Nicolas with challenging hetero-specific grafting experiments, and for her project, developed the use of comparative imaging in cultured skin tissues of various species of Ratites, Galliformes, and Penguins!
Pierre studied at the Ecole Normale Supérieure of Lyon where he obtained an agrégation in biology and geology. He then got familiar to pigmentation biology of colouration during an internship in Haruhiko Fujiwara's laboratory at the University of Tokyo in 2014. There, he studied the formation of color patterns in the skin of silkworms. He carried on with a Master in biology and complex systems and started his PhD in the lab in october 2018. Pierre studies the role of skin growth on the formation of striped, periodic color patterns in the dorsum of ratites and Galliformes, using both mathematical modelling and micro-manipulation, and experimental developmental biology, taking advantage in particular of electroporation and the production of skin explants. Will Pierre become the next "golden hands" of the lab? ;)
Carole Desmarquet Trin-Dinh
After a first experience in a private company, Carole moved on to academic research and got recruited by the INSERM. She worked at the Pasteur Institute to develop a papillomavirus vaccine (now on the market) in the laboratory of Gérard Orth. In 1994, she oriented her focus towards developmental biology at the Ecole Normale Supérieure of Paris, contributing to studies on the genetic control of the central and peripheral nervous system in vertebrates performed in the laboratory of Pr. Charnay. In 2017, she made again a bold carrier move: motivated by the prospect of studying patterning in another organ (the skin), she joined our team to complete her technical skills in developmental biology: from rattus norvegicus to the cottontail rabbit and mus musculus, and lastly the zebrafish, Carole now completes the "zebra" series with our dear zebra finches!
Marie maintains the 100 bird colony, making sure animals are well-fed, breeding and happy!
FORMER LAB MEMBERS
Born in beautiful Brittany and raised in equally beautiful Paris, Nicole has always been bound to biology: she worked as a laboratory technician in hospitals and biotech companies until 1996, where she was recruited as a research engineer at the Collège de France. There, she first integrated the team of Pr. Berthoz where she performed histological studies, and after obtaining her EPHE diploma (high practice studies) in 1999 she joined the neuro-imaging platform. She became its supervisor from 2000 to 2005, and as such, contributed to the development of the imaging technical facility of the Center. Her interest in research led her to recently redirect her career and integrate research teams, sharing her time between our laboratory and that of our dear microbiologists neighbors i.e., Dr. Olivier Espeli lab), which whom she works full time now... She still often comes to the end of the corridor to say hi!
Thanh-Lan is interested in studying the mechanisms shaping the evolution of animals forms and how diversity is constrained by developmental processes in bird plumage patterns using multidisciplinary methods, from embryology to evolutionary modeling. She completed her PhD in evolutionary biology in the laboratory of Dr. Mundy (Cambridge University) in 2014 and then moved to the laboratory of Dr. Thomas (Sheffield University) where she designed digital photography methods to study the coloration of 10000 species of birds in collaboration with Pr. Endler (Deakin University). She completed a one year postdoc in the Manceau laboratory in 2015 to examine how positional factors generate region-specific differences in various species of songbirds of the Estrildidae family. Thanh-Lan is now an independent researcher at Edinburgh University: we wish you the best Than-Lan! :)
Samantha obtained her License and Master I in bioengineering at the Paul Sabatier University of Toulouse in the South of France. She has worked since then as an Assistant engineer and laboratory technician in several public research institutions (Claudus Régaud Institute (Toulouse), Tenon Hospital, Georges Pompidou European Hospital (HEGP) and Vision's Intitute (Paris)) and pharmaceutical companies (Sanofi, Servier). She has contributed to biomedical research on cancer as well as kidney and vision diseases and fundamental scientific projects related to cell and molecular biology. She has thereby developed a broad palette of technical skills. She managed all technical aspects of the laboratory and supervised the maintenance of the bird facility. Samantha is now a lab manager at Cambridge University.
College des Ingenieurs, Paris, France