CURRENT LAB MEMBERS
Marie is CNRS Research Director (DR2). She is interested in studying the formation and evolution of patterns in the skin. She completed her PhD in avian developmental biology in the laboratory of Pr. Marcelle at the University of Marseille (France) in 2007, and then moved as a postdoc in the laboratory of Dr. Hoekstra at Harvard University, where she studied the developmental bases of color pattern variation in rodents. Since 2013, she is a Research Group Leader at the Collège de France (CIRB). Marie also works as a naturalist guide in the Arctic and Antarctica.
Carole Desmarquet Trin-Dinh
After a first experience in a private company, Carole moved on to academic research and got recruited by the INSERM. She worked at the Pasteur Institute to develop a papillomavirus vaccine (now on the market) in the laboratory of Gérard Orth. In 1994, she oriented her focus towards developmental biology at the Ecole Normale Supérieure of Paris, contributing to studies on the genetic control of the central and peripheral nervous system in vertebrates performed in the laboratory of Pr. Charnay. In 2017, she made again a bold carrier move: motivated by the prospect of studying patterning in another organ (the skin), she joined our team to complete her technical skills in developmental biology: from rattus norvegicus to the cottontail rabbit and mus musculus, and lastly the zebrafish, Carole now completes the "zebra" series with our dear zebra finches!
After obtaining a double bachelor degree in Biology and Philosophy at Sorbonne University, Coline chose to enrol in the ENS/PSL master of biology (IMALIS). At first interested in evolutionary biology, Coline discovered developmental biology during her 2020 internship at the Misaki Marine Biological Station of Tokyo University. There, she worked on post-embryonic development of Acoelomorpha. In January 2021 she joined our team to study the formation of color patterns : her goal is to identify the embryonic origin of periodic stripes in galliformes and ratites. Welcome to the lab Coline, may science be with you!
María Castro Scherianz
María performed her Master studies at the Ecole Normale Supérieure in Paris. Her undergrad and first year of master confirmed her interest in developmental biology through internships in which she worked on lab mice. For her second year of master degree she decided to switch gears and get to know birds! After two rotations in the lab and an internship in Marseille with the team of Pierre-François Lenne, she started her PhD in September 2022. Her project aims at characterising species-specific geometry of the feather follicle array according to body location, with the ultimate goal to link natural variation to differences in mechanical properties of the developing skin tissue. Welcome to the lab, and best of luck, María!
Independent Postdoc (ENS)
Arghyadip (Argo) is a theoretical physicist. By combining insights from mechanics, geometry and cell biology, he wants to understand how complex shapes arise in multicellular systems such as feather follicles. Before moving to Paris, he worked on hydrodynamic effects in oogenesis during his PhD at MPI-Dresden. Since March 2022, he is an independent postdoctoral fellow at Ecole Normale Supérieure of Paris and holds the QBio Junior Research Chair.
Nadia De Mota-Picco
Nadia holds a technical degree (BTS) in biotechnology. She joined the Collège de France in 1995 in the team of Dr.Llorens-Cortès, where she worked on developing a therapeutic approach to treat resistant arterial hypertension and on the physiological effects of apelin. She joined the Manceau team in September 2022. She takes care of laboratory logistics and studies the expression of candidate genes in the avian skin.
Romain performed his Master studies at the Sorbonne University of Paris. Curious to work with various models, he studied the neurodevelopment of jellyfish and the endocrine systems of amphibians and fish during his Master. He then decided to pursue a PhD in developmental biology, which he started in the lab in October 2023. His project aims at uncovering the mechano-chemical bases of species-specific feather array geometry. Straight from the get go, Romain performed field work and hard-core imaging, plunging directly into the core of our research approaches. Welcome to the team, Romain!
FORMER LAB MEMBERS
Julia is currently a student in a biomedical sciences degree program at the Université Paris Cité. She performs a 6 month internship in the lab, studying the molecular control of region-specific identity in the embryonic skin of poultry birds.
Pierre obtained a bachelor degree in biology at the university of Montpellier and joined the International Master of Life Sciences of Lyon University in 2022. After following a developmental biology class where Marie presented the work of the lab, he applied for a two-month internship (bravely facing countless administrative issues ;). He worked with María on the cellular events shaping the production of feather patterns in several species of birds.
After performing genomics work on human pathologies, Hélène got interested in evolutionary biology and studied cat pigmentation at the Jacques Monod Institute of Paris. She then joined our team in January 2022 for her double Master in Genetics and Biotechnology, respectively at the University of Paris cité and at the Bicocca University of Milan, to work on the colour of... cats prays! (i.e., birds). Her project involved surveying natural variation in colour domains across the bird phylogeny. Hélène works is now lab manager in the team of E. Fabre and P. Lesage at the Saint Louis Institute. She also continues to thrive as a science outreach enthusiast; she organises the fun and lively "Pint of Science" sessions, where one can learn about fantastic research while enjoying a drink ;)
Eddy maintained the 100 bird colony, making sure animals were well-fed, breeding and happy!
Camille joined the lab in January 2016 as part of her second year of Master's rotation student to study the origin of color domains in zebra finches using lineage techniques such as quail-zebra finch grafts and long-term electroporation. During her PhD, she describing the cell and tissue dynamics occurring during the formation of plumage macro- and micro-patterns. She became our "graft master" and developed the use of comparative imaging in cultured skin tissues of various species of Ratites, Galliformes, and Penguins! Camille defended her PhD on October 5th 2020, and after a short postdoc in the lab, moved on to Uri Frank's lab at Galway University, where she currently studies hydra development.
Nicolas completed his PhD in the laboratory of Dr. Yasuo at Nice University (Marine research station of Villefranche-sur-Mer). He characterized the function of Ephrin signaling pathways during neural fate specification and pigments cells formation in Ascidians. Nicolas joined the laboratory as a postdoc in February 2015: he was interested in the developmental regulation of periodic patterning in juveniles of galliformes and Ratites. His ultimate goal was to uncover the mystery of intricate geometric patterning. When not in the lab, you could find Nicolas riding his bike or fishing, or (albeit not so often in Paris) wearing a pair of skis.
After a postdoc with Jochen Rink at the Max Planck Institute for Biophysical chemistry, Nicolas joined the IRCAN Institute in Nice to study pattern formation in invertebrates.
Magdalena received her Ph.D. degree in 2011 from the Paris XIII University. She was advised by Pr. Beaudry in the laboratory of Pr. Richalet and in close collaboration with Pr. Darribère, and studied muscle differentiation in hypoxia in xenopus. She then worked during two years as a Research Assistant Lecturer at Paris V University, before joining the laboratory of Dr. Perron at Paris-Sud University for a first postdoc, where she focused on retina regeneration in amphibia. Magdalena joined the lab as a postdoctoral fellow in Febrary 2015 where she adapted her micromanipulation skills from her previous developmental studies in amphibia to work on the origin of positional factors shaping large color domains in zebra finches. Magda is currently looking for a permanent position in life science. We wish her the best of luck; we miss her skills as much as her smiles everyday!
Richard studied at the Ecole Normale Supérieure of Rennes where he passed his agrégation in mathematics. He discovered mathematical biology during an internship in Jonathan Touboul's laboratory at the Collège de France in 2013, where he designed models describing neural activity. He carried on with a Master in Mathematics applied to Life Sciences (Paris-Sud University) and a PhD in the lab, co-advised by Marie Manceau, Jonathan Touboul and Benoît Perthame (UPMC). Richard defended his thesis on July 10th 2019, and is now a postdoctoral fellow at EMBL Heidelberg in the laboratory of A. Ikmi.
His work in the lab mainly consisted in conceiving models describing developmental mechanisms underlying the formation of color and appendage patterns in birds of the Passeriformes, Galliformes, and Sphenisciformes orders. Richard was also the official lab cook, often feeding his lab mates with his famous "tarte au citron".
Pierre studied at the Ecole Normale Supérieure of Lyon where he obtained an agrégation in biology and geology. He then got familiar to pigmentation biology of colouration during an internship in Haruhiko Fujiwara's laboratory at the University of Tokyo in 2014. There, he studied the formation of color patterns in the skin of silkworms. He carried on with a Master in biology and complex systems and started his PhD in the lab in october 2018. Pierre studied the role of skin growth on the formation of striped, periodic color patterns in the dorsum of ratites and Galliformes, using both mathematical modelling and micro-manipulation, and experimental developmental biology, taking advantage in particular of electroporation and the production of skin explants. He currently performs a PhD at the MNHN Paris.
Marie maintained the 100 bird colony, making sure animals are well-fed, breeding and happy!
Born in beautiful Brittany and raised in equally beautiful Paris, Nicole has always been bound to biology: she worked as a laboratory technician in hospitals and biotech companies until 1996, where she was recruited as a research engineer at the Collège de France. There, she first integrated the team of Pr. Berthoz where she performed histological studies, and after obtaining her EPHE diploma (high practice studies) in 1999 she joined the neuro-imaging platform. She became its supervisor from 2000 to 2005, and as such, contributed to the development of the imaging technical facility of the Center. Her interest in research led her to recently redirect her career and integrate research teams, sharing her time between our laboratory and that of our dear microbiologists neighbors i.e., Dr. Olivier Espeli lab), which whom she works full time now... She still often comes to the end of the corridor to say hi!
Thanh-Lan is interested in studying the mechanisms shaping the evolution of animals forms and how diversity is constrained by developmental processes in bird plumage patterns using multidisciplinary methods, from embryology to evolutionary modeling. She completed her PhD in evolutionary biology in the laboratory of Dr. Mundy (Cambridge University) in 2014 and then moved to the laboratory of Dr. Thomas (Sheffield University) where she designed digital photography methods to study the coloration of 10000 species of birds in collaboration with Pr. Endler (Deakin University). She completed a one year postdoc in the Manceau laboratory in 2015 to examine how positional factors generate region-specific differences in various species of songbirds of the Estrildidae family. Thanh-Lan is now an independent researcher at Edinburgh University: we wish you the best Than-Lan! :)
Samantha obtained her License and Master I in bioengineering at the Paul Sabatier University of Toulouse in the South of France. She has worked since then as an Assistant engineer and laboratory technician in several public research institutions (Claudus Régaud Institute (Toulouse), Tenon Hospital, Georges Pompidou European Hospital (HEGP) and Vision's Intitute (Paris)) and pharmaceutical companies (Sanofi, Servier). She has contributed to biomedical research on cancer as well as kidney and vision diseases and fundamental scientific projects related to cell and molecular biology. She has thereby developed a broad palette of technical skills. She managed all technical aspects of the laboratory and supervised the maintenance of the bird facility. Samantha is now a lab manager at Cambridge University.
College des Ingenieurs, Paris, France